PT. HES Indomakmur Gemilang – Sodium Benzoate Purox, Sodium benzoate is a substance which has the chemical formula C6H5COONa. It is a widely used food preservative, with an E number of E211. It is the sodium salt of benzoic acid and exists in this form when dissolved in water. It can be produced by reacting sodium hydroxide with benzoic acid. Sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids.This leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo.
In combination with ascorbic acid (vitamin C, E300), sodium benzoate and potassium benzoate may form benzene. When tested by the FDA, most beverages that contained both ascorbic acid and benzoate had benzene levels that were below those considered dangerous for consumption by the World Health Organization (5 ppb).Most of the beverages that tested higher have been reformulated and subsequently tested below the safety limit. Heat, light and shelf life can increase the rate at which benzene is formed.